二氫羊毛甾醇 24,25-二氫羊毛甾醇醇

二氫羊毛甾醇

 24,25-二氫羊毛甾醇醇          CAS  911660-54-3         分子量428.73        分子式：C30H52O

純       度：     HPLC95%
物理性狀：     白色粉末
檢測方法：      高效液相（HPLC）質(zhì)譜（Mass) 核磁（NMR)
用      途：      僅供研究使用,不得用于醫(yī)學(xué)診斷。
包      裝：      5mg~1g 棕色玻璃瓶。
儲存條件：     貯存在避光密閉容器中，冷藏或者冷凍長期保存。
樣品溶液現(xiàn)配現(xiàn)用。如果特殊情況需要提前配制的話，最好分成獨立包裝冷凍保存（-20℃以下），臨用前再取出解凍，通?？梢员４?周。

來源
羊毛脂。

Description

• low-toxicity and high-yielding method for the production of pure lanosterol and dihydrolanosterol from the commercially available mixture. Optimum conditions are presented for the one-pot production of the intermediate 24,25 vicinal diol of lanosterol acetate (via either epoxidation or hydroxyhalogenation) which is readily separated from the unreacted dihydrolanosterol acetate. The lanosterol diol can then be converted to pure (>97%) lanosterol. Hypophosphorous acid was used for both the conversion of the epoxide to the diol, and as a catalyst for the hydroxyhalogenation by N-halosuccinimides of the olefinic bond

References

• [1]. Kavtaradze LK, Manley-Harris M, Nicholson BK. A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures.. PMID: 15465116